Amogus is a bastardized version of the name of the 2018 video game Among Us. In January 2021, the word gained popularity as a catchphrase used in ironic memes. It is often used to replace dialogue in cartoons and as a way of shitposting by spamming the phrase alongside sus.
Additionally, Amogus refers to the simplified drawing of a crewmate from Among Us used in the memes. This drawing has become a popular meme format.
In May 2021, the Amogus panel regained popularity as a pop culture and history reference format. The word was altered to three-syllable names ending with "us," such as "Columbus," and the panel was redrawn accordingly. - Source: KnowYourMeme